Introduction
Pefloxacin 400mg tablets are a commonly prescribed antibiotic medicine used to treat a variety of bacterial infections. Belonging to the fluoroquinolone group of antibiotics, Pefloxacin works by stopping the growth and spread of harmful bacteria in the body. Doctors often recommend this medicine when infections are moderate to severe and require strong antibacterial action.
Uses of Pefloxacin 400mg Tablets
Pefloxacin is mainly used to treat bacterial infections caused by susceptible microorganisms. Pefloxacin is not effective against viral infections like the common cold or flu.
Common uses include:
- Urinary Tract Infections (UTIs): Helps eliminate bacteria causing pain, burning, and frequent urination
- Respiratory Tract Infections, which include bronchitis or pneumonia caused by bacteria
- Gastrointestinal Infections: Including infections of the stomach and intestines
- Skin and Soft Tissue Infections: Treats bacterial skin conditions
- Bone and Joint Infections: Used in specific cases under medical supervision
- Sexually Transmitted Infections: Sometimes prescribed for certain bacterial STIs
Doctors may prescribe Pefloxacin when other antibiotics are not effective or suitable.
Ingredients in Pefloxacin 400mg
Each tablet contains: Pefloxacin Mesylate (equivalent to Pefloxacin 400mg) – the active ingredient responsible for fighting bacterial infections
How Pefloxacin Works
Pefloxacin works by targeting the DNA replication process of bacteria. Bacteria need to copy their DNA to grow and multiply. This medicine blocks the enzymes responsible for this process, known as DNA gyrase and topoisomerase IV. When these enzymes are blocked, bacteria cannot multiply, the infection stops spreading, and the immune system can eliminate the remaining bacteria. Because of this mechanism, Pefloxacin is effective against a wide range of bacteria and helps reduce infection symptoms within a few days when taken correctly.
Pefloxacin Dosage and How to Take Pefloxacin 400mg
The dosage of Pefloxacin depends on the type and severity of the infection, as well as the patient’s age, weight, and medical condition.
General dosage guidelines: Usually one 400mg tablet once or twice daily. Duration typically ranges from 5 to 14 days
Possible Side Effects of Pefloxacin
Like all medicines, Pefloxacin may cause side effects, although not everyone experiences them.
Common side effects include:
- Nausea or vomiting
- Stomach pain or diarrhea
- Headache
- Dizziness
- Loss of appetite
Less common but serious side effects:
- Severe allergic reactions (rash, itching, swelling)
- Tendon pain or swelling
- Severe diarrhea or bloody stools
- Mood changes or confusion
Frequently Asked Questions (FAQs)
1. Is Pefloxacin 400mg safe for everyone?
Pefloxacin is not suitable for everyone. It should be used with caution in people with liver problems, epilepsy, tendon disorders, or a history of allergic reactions to fluoroquinolones. Always inform your doctor about your medical history.
2. Can I take Pefloxacin with other medicines?
Some medicines may interact with Pefloxacin, including antacids, iron supplements, and certain painkillers. Keep a gap of at least 2 hours between Pefloxacin and antacids or supplements.
3. Can I drink alcohol while taking Pefloxacin?
It is best to avoid alcohol during treatment, as it may increase side effects like dizziness or stomach upset.
4. How long does Pefloxacin take to work?
Most people start feeling better within 2–3 days, but it is important to complete the full course to fully clear the infection.
5. Can pregnant or breastfeeding women take Pefloxacin?
This medicine is generally not recommended during pregnancy or breastfeeding unless clearly advised by a doctor.
Conclusion
Pefloxacin 400mg by 10 tablets is a powerful and effective antibiotic used to treat a wide range of bacterial infections. When taken correctly, it helps stop bacterial growth, reduces symptoms, and supports faster recovery. Understanding its uses, dosage, and possible side effects ensures safer and more effective treatment.
Always follow your doctor’s instructions, complete the prescribed course, and avoid self-medication. With proper use, Pefloxacin can play an important role in managing bacterial infections and restoring good health.
