AXITIN IV INJ 1.2G

AXITIN IV INJ 1.2G is a potent intravenous antibiotic formulation combining amoxicillin sodium and potassium clavulanate. This combination is designed to combat a broad spectrum of bacterial infections effectively.

Axitin IV Injection Composition

Each 1.2g vial contains:

Amoxicillin Sodium BP equivalent to 1000 mg of amoxicillin and
Potassium Clavulanate BP equivalent to 200 mg of clavulanic acid

This combination enhances the antibiotic’s efficacy against bacteria that produce beta-lactamase enzymes, which can otherwise render certain antibiotics ineffective.

Axitin IV Inj Uses

AXITIN IV INJ 1.2G is indicated for the treatment of various infections caused by susceptible bacteria, including:

Respiratory tract infections
Urinary tract infections
Skin and soft tissue infections
Bone and joint infections
Intra-abdominal infections
Gynecological infections
Additionally, it is utilized for surgical prophylaxis to prevent potential postoperative infections.

Axitin IV Inj Mode of Action

Amoxicillin, a penicillin-class antibiotic, works by inhibiting the synthesis of bacterial cell walls, leading to cell lysis and death. However, some bacteria produce beta-lactamase enzymes that can inactivate amoxicillin. Clavulanic acid acts as a beta-lactamase inhibitor, preventing the degradation of amoxicillin and thereby extending its spectrum of activity against resistant bacteria.

Axitin IV Inj Dosage and Administration

The dosage of AXITIN IV INJ 1.2G varies based on the severity and type of infection, as well as patient factors such as age and renal function.

For adults, the typical dose is 1.2 g administered every 8 hours. In more severe infections, the frequency may be increased to every 6 hours.
For surgical prophylaxis, a 1.2 g dose is given at the time of induction, with up to 2-3 additional doses of 1.2 g every 8 hours for high-risk procedures.
Dosage adjustments are necessary for patients with renal impairment.

Axitin IV Inj Side Effects

Diarrhea
Nausea
Skin rashes
Injection site reactions
Anaphylaxis
liver dysfunction

Axitin IV Inj Onset of Action

AXITIN IV INJ 1.2G is administered intravenously, allowing for rapid distribution and onset of action. Patients may begin to experience symptomatic relief within a few hours of administration, depending on the severity and location of the infection.

Can AXITIN IV INJ 1.2G be used in patients with penicillin allergies?

AXITIN IV INJ 1.2G contains amoxicillin, a penicillin derivative. It is contraindicated in patients with a history of hypersensitivity to penicillin or beta-lactam antibiotics due to the risk of severe allergic reactions.

How should AXITIN IV INJ 1.2G be stored?

The vials should be stored in a cool, dry place away from direct light. Reconstituted solutions should be used immediately or stored according to the manufacturer’s guidelines to maintain potency and prevent contamination.

Is AXITIN IV INJ 1.2G safe for use during pregnancy?

AXITIN IV INJ 1.2G should be used during pregnancy only if clearly needed and prescribed by a healthcare provider. It is essential to weigh the potential benefits against any possible risks to the fetus.

Can AXITIN IV INJ 1.2G be administered to children?

Yes, AXITIN IV INJ 1.2G can be used in pediatric patients. The dosage is typically based on the child’s body weight and the severity of the infection. A common regimen is 30 mg/kg administered every 8 hours, which may be increased to every 6 hours in more severe infections.