ARTESUNAT INJ

Artesunat Injection is a life-saving antimalarial medication designed for the treatment of severe malaria, particularly cases caused by Plasmodium falciparum, a parasite responsible for severe and life-threatening malaria infections. This injectable treatment is recommended for both adults and children, ensuring prompt relief and reducing malaria-related complications.

Uses of Artesunat Injection

Artesunat Injection is primarily used for:

Treating severe malaria caused by Plasmodium falciparum.
Managing cases where oral administration of antimalarial drugs is not possible.
Supporting quick recovery by eliminating parasites rapidly from the bloodstream.

Artesunat Injection Ingredients

The primary active ingredient in Artesunat Injection is artesunate.

Artesunat Injection Mode of Action

Artesunate, the active ingredient in Artesunat Injection, works by:

Generating reactive oxygen species (ROS) within the malaria parasite leads to oxidative stress.
Inhibiting the parasite’s ability to metabolize hemoglobin, a critical source of nutrients.
Disrupting the parasite’s lifecycle, leading to its destruction.

This mechanism ensures rapid clearance of the parasite from the bloodstream, making it a highly effective treatment for severe malaria.

Artesunat Injection Dosage

Adults and Children: 2.4 mg per kg of body weight administered intravenously or intramuscularly. The first dose is given at 0 hours, followed by doses at 12 and 24 hours. Daily doses are continued thereafter until the patient can transition to oral antimalarial therapy.

Artesunat Injection Side Effects

Nausea or vomiting.
Low blood pressure.
Dizziness or headache.
Temporary changes in liver function tests.
Rash
swelling

How Quickly It Works

Artesunat Injection starts working within hours of administration. Clinical studies have shown that artesunate clears the malaria parasite from the bloodstream within 24-48 hours, significantly reducing symptoms such as fever, chills, and weakness. Its rapid action is critical in preventing complications like cerebral malaria, organ failure, or death.

Is Artesunat Injection safe for pregnant women?

Yes, Artesunat Injection is considered safe for use during pregnancy, especially in cases of severe malaria.

Can Artesunat Injection be used for all types of malaria?

While it is most effective against Plasmodium falciparum, it can also be used in severe cases of other malaria types where oral therapy is not possible.

How long does treatment with Artesunat Injection last?

Treatment duration depends on the severity of malaria. Typically, patients are treated for 48-72 hours before transitioning to oral antimalarial therapy.