Uses of Aminophylline Injection
Aminophylline Injection is primarily used to treat conditions such as:
- Severe Asthma Attacks: It relaxes the airway muscles to improve breathing.
- Chronic Obstructive Pulmonary Disease (COPD): Helps relieve bronchospasms.
- Pulmonary Edema: Reduces symptoms caused by fluid accumulation in the lungs.
- Respiratory Distress Syndromes: Enhances respiratory function in critical cases.
Aminophylline Injection Ingredients
Each 10ml vial of Aminophylline Injection contains:
- Active Ingredient: Aminophylline 25mg/ml
- Inactive Ingredients: Sodium hydroxide, water for injection
These components are carefully formulated for intravenous use, ensuring maximum efficacy.
Aminophylline Injection Mode of Action
Aminophylline belongs to the xanthine class of drugs and works by:
- Relaxing Bronchial Muscles: It inhibits phosphodiesterase, increasing cAMP levels, which causes smooth muscle relaxation.
- Reducing Inflammation: Helps decrease airway sensitivity and swelling.
- Improving Oxygen Uptake: Enhances diaphragmatic contractility, making breathing more efficient.
This mechanism ensures rapid relief from respiratory symptoms.
Aminophylline Injection Dosage and Administration
Aminophylline Injection is typically administered by a healthcare professional in a hospital or emergency setting.
- Adults: Initial dose ranges between 5-6 mg/kg intravenously over 20 minutes. Maintenance doses depend on body weight and serum drug levels.
- Children: Doses are carefully calculated by body weight and monitored closely.
Aminophylline Injection Side Effects
While generally effective, Aminophylline Injection may cause some side effects, including:
- Nausea and vomiting
- Headache or dizziness
- Rapid heartbeat (tachycardia)
- Restlessness or anxiety
- Low blood pressure (hypotension) in rare cases
These effects are often mild but should be reported to a healthcare provider if they persist or worsen.
How Quickly Does Aminophylline Work?
Aminophylline Injection begins to act within 5-15 minutes after intravenous administration, offering rapid relief from severe respiratory distress. The peak effect occurs within an hour, making it ideal for emergency situations.
Is Aminophylline Injection safe for everyone?
Aminophylline is generally safe when administered under medical supervision. However, it is not recommended for individuals with a history of allergic reactions to xanthine derivatives, severe heart conditions, or peptic ulcers.
Can it be used during pregnancy?
Its use in pregnancy is typically reserved for cases where the benefits outweigh potential risks.
How is Aminophylline different from Theophylline?
Aminophylline is a compound of theophylline and ethylenediamine, which makes it more water-soluble and suitable for intravenous use.
Can I self-administer Aminophylline?
No, Aminophylline Injection should only be administered by qualified medical personnel in a controlled setting.
Where can you buy Aminophylline Inj in Nigeria?
You can purchase Aminophylline Inj online at Drugstore.ng, Nigeria’s largest online pharmacy store.
