ATROPINE SULPHATE INJ

Atropine Sulphate Injection is a highly effective medication widely used in medical emergencies and specific treatments. It belongs to the class of anticholinergic and antimuscarinic drugs and is essential in critical care settings.

Uses of Atropine Sulphate Injection

Atropine Sulphate Injection is used for:

Treating bradycardia (abnormally slow heart rate).
Counteracting poisoning by organophosphates and nerve agents.
Reducing secretions during surgery to improve airway management.
Managing spasms of the gastrointestinal and urinary tracts.
Pre-anesthetic medication to prevent excessive salivation and mucus production.

ATROPINE SULPHATE INJ Ingredients

The key ingredient in Atropine Sulphate Injection is atropine sulphate, a potent alkaloid derived from plants like Atropa belladonna. Each millilitre contains a specific concentration of atropine sulphate, typically 0.6 mg/mL, along with sterile water as the solvent. Additional stabilizers and preservatives may be present depending on the formulation.

ATROPINE SULPHATE INJ Mode of Action

Atropine works by blocking the action of acetylcholine, a neurotransmitter responsible for stimulating the parasympathetic nervous system. By inhibiting acetylcholine at muscarinic receptors, atropine reduces secretions, relaxes smooth muscles, and increases heart rate. This mechanism makes it particularly effective in emergency settings where rapid reversal of parasympathetic effects is critical.

ATROPINE SULPHATE INJ Dosage

For Bradycardia: Adults are typically administered 0.5 mg intravenously every 3-5 minutes, up to a maximum dose of 3 mg.
In Poisoning: Doses vary depending on severity, starting with 2-4 mg intravenously or intramuscularly and repeated as needed.
Pre-Anesthesia: A single dose of 0.4-0.6 mg is usually sufficient.
Always follow the prescribed dosage as directed by a healthcare professional.

ATROPINE SULPHATE INJ Side Effects

While Atropine Sulphate Injection is generally safe when administered correctly, some individuals may experience side effects, including:

Dry mouth and throat
Blurred vision
Increased heart rate (tachycardia)
Difficulty urinating
Constipation
Dizziness or confusion Severe adverse effects are rare but may include severe allergic reactions or overheating due to reduced sweating.

How Quickly Does ATROPINE SULPHATE INJ Work?

Atropine Sulphate Injection works rapidly, typically within 1-2 minutes when administered intravenously. Its effects can last for 30-60 minutes, depending on the dose and purpose of use.

Can Atropine Sulphate be used in children?

Yes, it is safe for pediatric use when administered by a healthcare professional. The dosage will be adjusted based on the child’s weight and condition.

Is Atropine Sulphate Injection available over the counter?

No, this medication requires a prescription and must be administered by a qualified healthcare provider.

Are there any contraindications for Atropine?

Yes, Atropine is contraindicated in patients with glaucoma, myasthenia gravis, obstructive uropathy, or severe tachycardia unless absolutely necessary.