Amikacin Injection, branded as Sefkin, is a powerful antibiotic used to treat a wide range of bacterial infections. Its high efficacy makes it a trusted solution for combating severe infections that other antibiotics may fail to treat.
Uses of Amikacin Injection (Sefkin)
Amikacin is primarily used for treating serious bacterial infections, which includes
- Respiratory infections such as pneumonia.
- Urinary tract infections (UTIs)
- Intra-abdominal infections like peritonitis.
- Bone and joint infections, such as osteomyelitis.
- Sepsis and other blood-borne bacterial infections.
- Skin and soft tissue infections, which include burns and surgical site infections.
This injection is often administered in hospital settings under strict medical supervision.
Amikacin sulfate Ingredients
The active ingredient in Sefkin is Amikacin sulfate, a potent aminoglycoside antibiotic. Each vial typically contains Amikacin sulfate as the active antibacterial agent.
Amikacin sulfate Mode of Action
Amikacin works by inhibiting bacterial protein synthesis. It binds to the 30S ribosomal subunit of the bacteria, disrupting the production of essential proteins necessary for bacterial growth and replication. This action ultimately kills the bacteria, making it highly effective against gram-negative bacteria and some gram-positive strains.
Amikacin Sulfate Dosage and Administration
- Typical dosage: The standard dose for adults is 15 mg/kg/day, divided into two or three doses.
- Method of administration: It is given via intramuscular (IM) or intravenous (IV) injection.
- Duration: Treatment duration varies but usually lasts 7–10 days, depending on the severity of the infection.
- Pediatric use: Dosage for children is calculated based on weight and must be determined by a healthcare professional.
Always follow your doctor’s prescription and do not self-administer this medication.
Amikacin sulfate Side Effects
- Nausea and vomiting.
- Skin rash or allergic reactions.
- Injection site pain or irritation.
- Ototoxicity (Hearing loss or ringing in the ears).
- Kidney function impairment (nephrotoxicity).
- Dizziness or balance issues.
How Quickly Does It Work?
Amikacin Injection starts working within a few hours of administration. Improvement in symptoms with Amikacin injection is often noticeable within 48–72 hours. However, completing the full course of treatment is crucial to prevent bacterial resistance.
Is Amikacin Injection safe during pregnancy?
Amikacin should be used during pregnancy only if clearly needed and prescribed by a doctor. Its potential risks and benefits must be carefully weighed.
Can I use Amikacin Injection for viral infections?
No, Amikacin is effective only against bacterial infections and does not work for viral illnesses like the flu or common cold.
Where can you buy Amikacin Injection in Nigeria?
You can buy Amikacin injection online at Drugstore.ng, Nigeria’s largest online pharmacy store.
