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Prandin 0.5mg Tab X30

What is Prandin (repaglinide)?

Prandin (repaglinide) is an antidiabetic drug that belongs to the class of medications referred to as meglitinide. It was first introduced in 1983. Repaglinide is an oral diabetes drug that is used in combination with diet and exercise to reduce blood sugar levels in people with type 2 diabetes mellitus.

High blood sugar control can help avoid kidney damage, blindness, nerve disorders, limb loss, and sexual function complications. Diabetic management can also reduce the chances of having a heart attack or stroke. It works by inducing the production of more insulin in the body. Insulin is a naturally occurring compound that enables the body to better use sugar from food.

PRANDIN should not be used in the treatment of diabetic ketoacidosis or in patients with type 1 diabetes.

Prandin is a brand name with its generic name as Repaglinide. Repaglinide is an off-white powder with a molecular weight of 452.6 and the molecular formula C27H36N2O4.

 PRANDIN tablets contain repaglinide in doses of 0.5 mg, 1 mg, or 2 mg. In addition, each tablet contains the inactive ingredients mentioned below: Microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer.

Prandin (Repaglinide) Mechanism Of Action (MOA)

By inducing the release of insulin from the pancreas, repaglinide reduces blood glucose levels. This action depends on the  functioning beta (ß) cells in the pancreatic islets.   Insulin secretion is glucose-dependent and decreases at low glucose levels.

Prandin Classification (What class of drug is Prandin?)

PRANDIN (repaglinide) is an oral blood glucose-lowering medication of the glinide class

How long does it take for Prandin to work?

Repaglinide begins to work in 30 minutes to an hour.

Prandin half-life

Within 4 to 6 hours, repaglinide is fully removed from the bloodstream. The plasma elimination half-life is approximately one hour. Repaglinide is almost fully metabolized, and no clinically significant hypoglycaemic metabolites have been reported.

What are the side effects of Prandin?

Some of the common side effects of Prandin include weight gain,nausea,joint pain, back pain, diarrhea,nausea, runny nose or sneezing.

Is Prandin safe?

According to diabetes journal, In type 2 diabetic patients with renal impairment, repaglinide has a clear safety and efficacy profile and is an effective treatment option, even  for those with more serious degrees of renal impairment.

Is Prandin Insulin?

 Prandin (repaglinide) is not exactly an insulin but an oral diabetes medicine that stimulates the production of insulin by the pancreas by controlling the blood sugar level.

Can you take Prandin with Metformin?

Prandin (repaglinide) together with metformin should not be taken with gemfibrozil or NPH insulin (such as isophane insulin). 

How much does Prandin cost?

PRANDIN 0.5MG TAB X30 available on, Nigeria’s online pharmacy. Check the price of prandin here.


When should you take Prandin?

0.5 mg to 4 mg taken with meals is the recommended dosage range. In response to changes in the patient’s meal pattern, PRANDIN can be dosed preprandially 2, 3, or 4 times a day. The maximum daily dose is recommended to be 16 mg.

Generally, Prandin does not have fixed dosage for the treatment of type 2 diabetes. It is best to follow the physician’s advice and recommendations.

Directions To Use

Prandin is normally taken two to four times a day, 30 minutes before a meal. Pay attention to the doctor’s instructions. Do not take your Prandin dose if you miss a meal. You can wait for your next meal.


Content on should not be taken as prescription or medical advice. Consult your doctor or pharmacist before using any medication. 


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