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Phenoxymethylpenicillin is a type of penicillin antibiotic used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by penicillin G-sensitive microorganisms. It is also used for preventing infections if you have sickle cell disease, or if you have had chorea (a movement disorder), rheumatic fever, or your spleen removed.

Phenoxymethylpenicillin Ingredient 

Active Ingredient: phenoxymethylpenicillin potassium 

How Phenoxymethylpenicillin Works 

Phenoxymethylpenicillin is effective against microorganisms sensitive to penicillin, exhibiting bactericidal properties. It acts by disrupting the synthesis of peptidoglycan in the bacterial cell wall, specifically targeting the bacteria during their active replication stage.

Dosage and Direction of Use of Phenoxymethylpenicillin


The usual dosage recommendations are as follows:

Adults and children12 years and above: Take 250-500 mg every six hours

Children: Give Infants (up to 1 year): 62.5mg every 6 hours

1-5 years: Give 125 mg every six hours

6-12 years: Give 250 mg every six hours

Direction of Use 

Phenoxymethylpenicillin is meant for oral use exclusively.

The appropriate dosage and frequency of Phenoxymethylpenicillin depend on the severity and site of the infection, as well as the anticipated causative microorganisms.

It is recommended to take Phenoxymethylpenicillin Solution at least 30 minutes before or 2 hours after eating, as consuming it with meals may slightly hinder the drug’s absorption.

Phenoxymethylpenicillin Side Effects 

  • Nausea 
  • Vomiting 
  • Abdominal pain 
  • Diarrhea 
  • Skin reactions 
  • Rash

How Quickly Does phenoxymethylpenicillin Start to Work?

You should start to get better after taking this medicine for 2-3 days

When is the Best Time To Take Phenoxymethylpenicillin?

If you’re on a twice-daily dosing schedule, ensure there’s a 12-hour gap between each dose. For instance, you might take it at 8 AM and 8 PM. It’s advisable to avoid taking phenoxymethylpenicillin during mealtimes, as food can potentially affect its effectiveness. Instead, take it 30 minutes before a meal or wait at least 2 hours after eating before taking the medication.

Is it safe to use paracetamol alongside phenoxymethylpenicillin?

If you require pain relief or fever reduction while on penicillin, you can safely use over-the-counter pain relievers like paracetamol or ibuprofen. Penicillin does not interfere with hormonal contraceptives like birth control pills 

What is the Price of Phenoxymethylpenicillin in Nigeria?

The price of Phenoxymethylpenicillin is listed as ₦18,000 on 

Where can you buy Phenoxymethylpenicillin in Nigeria?

Buy Phenoxymethylpenicillin online at, Nigeria’s largest online pharmacy store.

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